In the field of nutrition, histidine is considered to be a human essential amino acid, mainly in children. After many years of development, humans can begin to synthesize it by itself, and at this time become a non-essential amino acid. In the diet of patients with chronic uremia, a small amount of histidine is added, the rate of amino acid binding into hemoglobin is increased, and renal anemia is reduced, so histidine is also an essential amino acid in uremic patients. Under the action of histidine decarboxylase, histidine is decarboxylated to form histamine. Histamine has a strong vasodilating effect and is associated with a variety of allergies and inflammation. In addition, histamine stimulates pepsin and stomach acid.

Functions of Histidine

1.L-Histidine is an essential amino acid that cannot be formed by other nutrients, and must be in the diet to be available to the body.

2.Most often recognized as a precursor to the allergy symptom producing hormone histamine, both histidine and histamine have essential roles in the body beyond tormenting allergy sufferers.

3.Histamine is well known for its role in stimulating the inflammatory response of skin and mucous membranes such as those found in the nose - this action is essential in the protection of these barriers during infection.

4.Histamine also stimulates the secretion of the digestive enzyme gastrin. Without adequate histamine production healthy digestion can become impaired. Without adequate L-histidine stores, the body cannot maintain adequate histamine levels.

5.Less well known is that L-histidine is required by the body to regulate and utilize essential trace minerals such as copper, zinc, iron, manganese and molybdenum.