Hot selling raw materials Tofacitinib CAS 477600-75-2 Powder CAS NO.477600-75-2

Min.Order: 1 Kilogram
Payment Terms: L/C,T/T,Other

Product Details

Keywords

Tofacitinib
CP-690550
Tofacitinib Powder

Quick Details

ProName: Hot selling raw materials Tofacitinib ...
CasNo: 477600-75-2
Molecular Formula: C16H20N6O
Appearance: White powder
Application: Pharma grade & Food grade
DeliveryTime: Ship out with in 3 days after confirmi...
PackAge: 1kg/bag; 25kg/drum, or as customer's r...
Port: Shanghai, Beijing, Guangzhou, HK
ProductionCapacity: Metric Ton/Day
Purity: 99%
Storage: Far from fire and heat, keep in cool p...
Transportation: DHL, EMS, FedEx, TNT, AIR, SEA
LimitNum: 1 Kilogram
Related Substances: Related impurities shall be not more t...
Residue on Ignition: 0.50%
Heavy Metal: <10ppm
Valid Period: 24 months

Superiority

Before-Sale Service:

---Any inquiries will be replied within 12 hours.
---Golden Manufactory under ISO/GMP with large stock.
---Dedication to quality,We have strict quality control system.
---OEM/ODM Available.
---Sample is available for your evaluation & Formulation development.
---Low MOQ: No worry about the big MOQ.
---Fast Delivery: Narmolly grt it within 7-10 days after confirming the order.
---Convenient Payment: Trade Assurance on Alibaba(Visa or Credit card), or TT

After-Sale Service:

---International Authorized Third-Party Test For The Products You Demand.
---60 Days Warranty of quality of goods.

What's more:
Looking forward to having a long-term cooperation with us in China !
Welcome to visit our factory ! ! !

Details

Tofacitinib (formerly tasocitinib, CP-690550) is a drug being investigated by Pfizer for the treatment of rheumatoid arthritis (RA), psoriasis, inflammatory bowel disease, and other immunological diseases, as well as for the prevention of organ transplant rejection. It is an inhibitor of the enzyme Janus kinase 3 (JAK3), which means that it interferes with the JAK-STAT signaling pathway that transmits information outside the cell into the cell nucleus, influencing DNA transcription. Recently it has been shown in a murine model of established arthritis, tofacitinib rapidly improved disease by inhibiting the production of inflammatory mediators and suppressing STAT1-dependent genes in joint tissue. This efficacy in this disease model correlated with the inhibition of both JAK1 and 3 signaling pathways, suggesting that tofacitinib may exert therapeutic benefit via pathways that are not exclusive to inhibition of JAK3.

GMP Factory Supply High Purity Tofacitinib Citrate powder with Best price

Before-Sale Service:

---Any inquiries will be replied within 12 hours.
---Golden Manufactory underISO/GMPwithlarge stock.
---Dedication to quality,Wehavestrictqualitycontrolsystem.
---OEM/ODM Available.
---Sample is available for your evaluation & Formulation development.
---LowMOQ: NoworryaboutthebigMOQ.
---FastDelivery: Narmolly grt it within 7-10 days after confirming the order.
---Convenient Payment: Trade Assurance on Alibaba(Visa or Credit card), or TT

After-Sale Service:

---International Authorized Third-Party Test For The Products You Demand.
---60 Days Warranty of quality of goods.

What's more:
Looking forward to having a long-term cooperation with us in China !
Welcome to visit our factory ! ! !

Xi'an Harmonious Natural Bio-Technology Co., Ltd.