98% min Vildagliptin powder with factory price CAS 274901-16-5 CAS NO.274901-16-5
- FOB Price: USD: 40.00-40.00 /Kilogram Get Latest Price
- Min.Order: 1 Metric Ton
- Payment Terms:
- Available Specifications:
AAAAA(1-25)Kilogram
- Product Details
Keywords
- Vildagliptin
- Vildagliptin powder
- 274901-16-5
Quick Details
- ProName: 98% min Vildagliptin powder with facto...
- CasNo: 274901-16-5
- Molecular Formula: C17H25N3O2
- Appearance: White powder
- Application: Pharma grade & Food grade
- DeliveryTime: Ship out with in 3 days after confirmi...
- PackAge: 1kg/bag; 25kg/drum, or as customer's r...
- Port: Shanghai, Beijing, Guangzhou, HK
- ProductionCapacity: Metric Ton/Day
- Purity: 98%
- Storage: Far from fire and heat, keep in cool p...
- Transportation: DHL, EMS, FedEx, TNT, AIR, SEA
- LimitNum: 1 Metric Ton
- Related Substances: Related protein shall be not more than...
- Residue on Ignition: 0.05%
- Heavy Metal: <10ppm
- Valid Period: 24 months
- Product name: Vildagliptin powder
- Appearance: white powder
- CAS: 274901-16-5
- molecular weight: 303.4
- molecular formula: C17H25N3O2
Superiority
Before-Sale Service:
---Any inquiries will be replied within 12 hours.
---Golden Manufactory under ISO/GMP with large stock.
---Dedication to quality,We have strict quality control system.
---OEM/ODM Available.
---Sample is available for your evaluation & Formulation development.
---Low MOQ: No worry about the big MOQ.
---Fast Delivery: Narmolly grt it within 7-10 days after confirming the order.
---Convenient Payment: Trade Assurance on Alibaba(Visa or Credit card), or TT
After-Sale Service:
---International Authorized Third-Party Test For The Products You Demand.
---60 Days Warranty of quality of goods.
What's more:
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Details
Vildagliptin is a selective, competitive and reversible DPP24 inhibitor. Glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like polypeptide 1 (GLP-1) are important hormones to maintain glucose concentration in the body, and both have incretin effects. The insulin-stimulating effect of GIP in patients with type 2 diabetes is impaired, and only GLP-1 can play the role of insulin-stimulating hormone secretion. GLP-1 also inhibits glucagon secretion and suppresses gastric emptying to increase satiety (suppression of appetite). DPP24 binds to proteins and exists in many tissues, such as kidney, liver, brush border of small intestinal membrane, pancreatic duct, lymphocytes, endothelial cells, and it can rapidly degrade GLP-1 by hydrolyzing the N-terminal 2 alanine of GLP-1. inactivated. This product inhibits the activity of this enzyme by combining with DPP24 to form a DPP24 complex. It increases the concentration of GLP-1 and promotes the production of insulin by islet β cells, while reducing the concentration of glucagon, thereby reducing blood sugar. and had no significant effect on body weight.
English name: Vildagliptin
CAS number: 274901-16-5
Molecular formula: C17H25N3O2
Molecular weight: 303.4 [1]
Melting point: 153-155℃
In conclusion, vildagliptin can reduce fasting and postprandial blood glucose levels, postprandial glucagon secretion and improve B cell function, providing a new option for the treatment of patients with type 2 diabetes. The safety and efficacy, contraindications, adverse reactions, etc. of the drug in combination with other drugs need to be observed in more clinical studies.
[Storage] Stored in a clean, cool and dry area; keep away from strong, direct light.
[Shelf Life] 2 years when properly stored.
[Packing]
Inner double plastic bags--25kg/Fiber drum (35*35*53cm, GW: 28kg, NW: 25kg, 0.06CBM);
Inner double plastic bags--5kg/Aluminum foil bag (GW: 6.5kg, NW: 5kg);
Inner double plastic bags--1kg/Aluminum foil bag (GW: 1.5kg, NW: 1kg).
[Delivery] 5 working days after payment.