Xi'an Harmonious Natural Bio-Technology Co., Ltd.

Xi'an Harmonious Natural Bio-Technology Co., Ltd.

Country: China (Mainland)Business Type: Lab/Research institutions

Manufacturer

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Contact US
Ms.Beryl
Tel: +86-18092068319
Ms.Vicky
Tel: 0086 29 86712509
Ms.Sara
Tel: 008618292978289
Mr.Marshall
Tel: +86 1569190561
  • Fax: +86 86712509
  • URL: http://www.xahnb.com
  • Province/state: shaanxi
  • City: Xi'an
  • Street:huilinhuacheng 10-2104
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Supply High Quality Cyproheptadine Hydrochloride Best Price

Supply High Quality Cyproheptadine Hydrochloride Best Price CAS NO.41354-29-4

  • Min.Order: 1 Kilogram
  • Payment Terms: L/C,T/T,Other
  • Product Details

Keywords

  • Cyproheptadine Hydrochloride
  • Cyproheptadine Hydrochloride Best Price
  • Supply High Quality Cyproheptadine Hydrochloride

Quick Details

  • ProName: Supply High Quality Cyproheptadine Hyd...
  • CasNo: 41354-29-4
  • Molecular Formula: C22H24N2O8.HClC21H21N.HCl
  • Appearance: White powder
  • Application: Pharma grade & Food grade
  • DeliveryTime: Ship out with in 3 days after confirmi...
  • PackAge: 1kg/bag; 25kg/drum, or as customer's r...
  • Port: Shanghai, Beijing, Guangzhou, HK
  • ProductionCapacity: Metric Ton/Day
  • Purity: 99%
  • Storage: Far from fire and heat, keep in cool p...
  • Transportation: DHL, EMS, FedEx, TNT, AIR, SEA
  • LimitNum: 1 Kilogram
  • Related Substances: Related impurities shall be not more t...
  • Residue on Ignition: 0.50%
  • Heavy Metal: <10ppm
  • Valid Period: 24 months

Superiority

Before-Sale Service:

---Any inquiries will be replied within 12 hours.
---Golden Manufactory under ISO/GMP with large stock.
---Dedication to quality,We have strict quality control system.
---OEM/ODM Available.
---Sample is available for your evaluation & Formulation development.
---Low MOQ: No worry about the big MOQ.
---Fast Delivery: Narmolly grt it within 7-10 days after confirming the order.
---Convenient Payment: Trade Assurance on Alibaba(Visa or Credit card), or TT

After-Sale Service:

---International Authorized Third-Party Test For The Products You Demand.
---60 Days Warranty of quality of goods.

What's more:
Looking forward to having a long-term cooperation with us in China !
Welcome to visit our factory ! ! !

Details

Cyproheptadine hydrochloride cas 41354-29-4

CAS No.: 41354-29-4

EINECS No.: 213-535-1

Molecular Formula: C21H22ClN

Molecular Weight: 323.86

Melting point: 165 °C (dec.)(lit.)

Appearance: white to light yellow crystalline powder

Standard: Enterprise Standard

 

Indication

For treatment of perennial and seasonal allergic rhinitis, vasomotor rhinitis, allergic conjunctivitis due to inhalant allergens and foods, mild uncomplicated allergic skin manifestations of urticaria and angioedema, amelioration of allergic reactions to blood or plasma, cold urticaria, dermatographism, and as therapy for anaphylactic reactions adjunctive to epinephrine  

 

 

Main function:

Cyproheptadine is a piperidine antihistamine. Unlike other antihistamines, this drug also antagonizes serotonin receptors. This action makes Cyproheptadine useful in conditions such as vascular headache and anorexia. Cyproheptadine does not prevent the release of histamine but rather competes with free histamine for binding at HA-receptor sites. Cyproheptadine competitively antagonizes the effects of histamine on HA-receptors in the GI tract, uterus, large blood vessels, and bronchial smooth muscle. Most antihistamines possess significant anticholinergic properties, but Cyproheptadine exerts only weak anticholinergic actions. Blockade of central muscarinic receptors appears to account for Cyproheptadine's antiemetic effects, although the exact mechanism is unknown. Cyproheptadine also competes with serotonin at receptor sites in smooth muscle in the intestines and other locations. Antagonism of serotonin on the appetite center of the hypothalamus may account for Cyproheptadine's ability to stimulate appetite. Cyproheptadine also has been used to counter vascular headaches, which many believe are caused by changes in serotonin activity, however it is unclear how Cyproheptadine exerts a beneficial effect on this condition.

Cyproheptadine hydrochloride

 

Cyproheptadine is a first-generation antihistamine with additional anticholinergic, antiserotonergic, and local anesthetic properties.

Cyproheptadine is used to treat allergic reactions (specifically hay fever).

Has shown effectiveness in the treatment of nightmares including nightmares related to post traumatic stress disorder.

Has been used in the management of moderate to severe cases of serotonin syndrome (a complex of symptoms associated with the use of serotonergic drugs, such as selective serotonin reuptake inhibitors and monoamine oxidase inhibitors), and in cases of hyperserotoninaemia resulting from a serotonin producing carcinoid tumour

Can also be used as a preventive measure against migraine in children and adolescents.

Can relieve SSRI-induced sexual dysfunction and drug-induced hyperhidrosis (excessive sweating).

Also used in the treatment of cyclical vomiting syndrome and to stimulate the appetite.

Items

Acceptance criteria

Results

Character

Appearance: White or almost white powder.

Almost white powder

Solubility: Slightly soluble in water, freely

soluble in dilute acetic acid and in methanol,

slightly soluble in alcohol.

Complies

Identification

A.Specific optical rotation: –30.0º~-33.5º

(dried substance)

–33.3º

B.Infrared absorption spectrophotometry:

The IR spectrum is consistent with that

obtained with Levodropropizine CRS.

Complies

Tests

pH

9.2~10.2

9.4

Impurity B and related

substances

Impurity B:  0.5%

 0.1%

Any other impurity:  0.1 %

 0.1%

Total impurities:  0.6 %

 0.1%

Impurity C

 5 ppm

 5ppm

Enantiomeric purity

Impurity A:  2 %

0.2 %

Loss on drying

 1.0 %.

 0.1%

Sulphated ash

 0.2 %

 0.1%

Assay

98.5%~ 101.0%(dried substance)

99.7%

Conclusion

The product meets the specification of EP7.0

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Before-Sale Service:

---Any inquiries will be replied within 12 hours.
---Golden Manufactory underISO/GMPwithlarge stock.
---Dedication to quality,Wehavestrictqualitycontrolsystem.
---OEM/ODM Available.
---Sample is available for your evaluation & Formulation development.
---LowMOQ: NoworryaboutthebigMOQ.
---FastDelivery: Narmolly grt it within 7-10 days after confirming the order.
---Convenient Payment: Trade Assurance on Alibaba(Visa or Credit card), or TT

After-Sale Service:

---International Authorized Third-Party Test For The Products You Demand.
---60 Days Warranty of quality of goods.

What's more:
Looking forward to having a long-term cooperation with us in China !
Welcome to visit our factory ! ! !

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